By Tuan A. Dinh, David P. Warshal (auth.), Eytan R. Barnea MD, FACOG, Eric Jauniaux MD, PhD, Peter E. Schwartz MD, FACOG (eds.)
Cancer and Pregnancy covers the medical demanding situations to diagnosing and treating malignancies within the pregnant sufferer; despite the fact that, the ebook additionally indicates how an realizing of the typical beneficial properties of either techniques (rapid mobilephone proliferation) could lead to novel anti-cancer healing procedures. The booklet may be learn by way of obstetricians and gynaecologists, scientific oncologists, copy experts, and people interested in research of improvement, biology, toxicology, immunology, in addition to melanoma research.
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Additional info for Cancer and Pregnancy
Techniques for performing cervical smears for pregnant women differ little from standard smears. The surface of the ectocervix should be sampled thoroughly and a specimen of endocervical cells collected. Use of the cytobrush and cervical brooms to collect endocervical cells has been controversial, given the potential risks of bleeding from the cervix and injury to the pregnancy. However, two randomized prospective trials have demonstrated that more abrasive techniques for collecting endocervical cells, such as the cytobrush, increase the yield of endocervical cells and decrease the frequency of inadequate smears without additional complications.
Hum Reprod 11:1620-6 Bonadonna G, Valagussa P, Moliterni A, Zambetti M, Brambilla C (1995). Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer: the results of 20 years of follow-up. N Eng! J Med 332(14):901-6 Bonnier P, Romain S, Dilhhuydy JM, et a!. (1997). Influence of pregnancy on the outcome of breast cancer: a case-control study. Int J Cancer 72:720-7 Botelho F and Clark DA (1998). How might pregnancy immunize against breast cancer? Am J Reprod ImmunoI39(4):279-83 Brook CGD and Marshall NJ (1996).
Once a breast symptom or sign has been noted the methods of investigation are similar to those followed in the non-pregnant woman. A thorough clinical history and examination should be followed by tissue sampling by means of fine needle aspiration cytology (Sorosky and Scott-Conner 1998), corecut biopsy or excision biopsy. Imaging techniques such as mammography and ultrasound are often not useful in this group of patients. Physiologic changes in the breast make mammography more clifficult to perform and to interpret during pregnancy.